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Tbio
ZFP42
Zinc finger protein 42 homolog

Protein Summary
Description
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326866
  • ENSP00000317686
  • ENSG00000179059
  • ENST00000509524
  • ENSP00000424662
  • ENST00000618147
  • ENSP00000483363

Symbol
  • REX1
  • ZNF754
  • REX1
  • REX-1
  • ZNF754
  • zfp-42
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.67
biological process
0.59
gene perturbation
0.59
virus perturbation
0.59
transcription factor
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.93   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 328   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.93   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 328   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (17)
Items per page:
10
1 – 9 of 9
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (57)
1 – 10 of 57
SUMO1
Tbio
Novelty: 0.00169202
Score: 0.835
Data Source: STRINGDB
NANOG
Tbio
Family: TF
Novelty: 0.00073323
Score: 0.812
Data Source: STRINGDB
POU5F1
Tbio
Family: TF
Novelty: 0.000425
Score: 0.803
Data Source: STRINGDB
ESRRB
Tchem
Family: NR
Novelty: 0.0096936
Score: 0.715
Data Source: STRINGDB
SOX2
Tbio
Family: TF
Novelty: 0.00050367
Score: 0.715
Data Source: STRINGDB
UTF1
Tbio
Novelty: 0.02642497
Score: 0.693
Data Source: STRINGDB
FGF5
Tbio
Novelty: 0.00817588
Score: 0.666
Data Source: STRINGDB
TDGF1
Tbio
Novelty: 0.00598943
Score: 0.665
Data Source: STRINGDB
DPPA5
Tbio
Novelty: 0.16921166
Score: 0.662
Data Source: STRINGDB
GDF3
Tbio
Novelty: 0.01421572
Score: 0.657
Data Source: STRINGDB
Publication Statistics
PubMed Score  18.93

PubMed score by year
PubTator Score  13.24

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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