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Tdark
PRRC1
Protein PRRC1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296666
  • ENSP00000296666
  • ENSG00000164244
  • ENST00000442138
  • ENSP00000392873
  • ENST00000512635
  • ENSP00000421965
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
disease perturbation
0.96
kinase perturbation
0.88
histone modification site profile
0.68
microRNA
0.67


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.94   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 54   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.94   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 54   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
response to antipsychotic drug
1
1
0
5.6
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
response to antipsychotic drug
0
5.6
35
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
proline rich coiled-coil 1
VGNC:13585
471618
Macaque
proline rich coiled-coil 1
704248
Mouse
MGI:1916106
73137
Rat
RGD:1565632
291444
Dog
proline rich coiled-coil 1
VGNC:45051
481489
Species
Name
OMA
EggNOG
Inparanoid
Chimp
proline rich coiled-coil 1
Macaque
proline rich coiled-coil 1
Mouse
Rat
Dog
proline rich coiled-coil 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96M27-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (43)
1 – 10 of 43
PLK1
Tchem
Family:  Kinase
Novelty:  0.00062799
p_int:  0.993576501
p_ni:  0.006423498
p_wrong:  1e-9
Data Source:  BioPlex
FUOM
Tbio
Family:  Enzyme
Novelty:  0.0562349
p_int:  0.94066988
p_ni:  0.059322649
p_wrong:  0.000007471
Score:  0.189
Data Source:  BioPlex,STRINGDB
SNRNP27
Tbio
Novelty:  0.0175187
p_int:  0.928588145
p_ni:  0.071410087
p_wrong:  0.000001767
Data Source:  BioPlex
FYTTD1
Tbio
Novelty:  0.04600073
p_int:  0.903081363
p_ni:  0.096491398
p_wrong:  0.000427238
Score:  0.184
Data Source:  BioPlex,STRINGDB
FSD1
Tbio
Novelty:  0.03452477
p_int:  0.903081363
p_ni:  0.096491398
p_wrong:  0.000427238
Data Source:  BioPlex
HADHA
Tbio
Novelty:  0.00385746
p_int:  0.863603603
p_ni:  0.135844938
p_wrong:  0.000551459
Data Source:  BioPlex
SDC1
Tbio
Novelty:  0.00044792
p_int:  0.799325074
p_ni:  0.138421465
p_wrong:  0.062253461
Score:  0.185
Data Source:  BioPlex,STRINGDB
PAFAH1B2
Tchem
Family:  Enzyme
Novelty:  0.07918203
Score:  0.869
Data Source:  STRINGDB
PSMG1
Tbio
Novelty:  0.08175356
Score:  0.866
Data Source:  STRINGDB
RHOA
Tbio
Family:  Enzyme
Novelty:  0.00022204
Score:  0.813
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.94

PubMed score by year
PubTator Score  1.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer