Tbio DHRS1 Dehydrogenase/reductase SDR family member 1

Protein Summary

Description

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

Uniprot Accession IDs

• Q96LJ7
• D3DS71
• Q8NDG3
• Q96B59
• Q96CQ5

Gene Name

• DHRS1

Ensembl ID

• ENST00000288111
• ENSP00000288111
• ENSG00000157379
• ENST00000396813
• ENSP00000380027
• ENST00000644514
• ENSP00000496132
• ENSG00000284868
• ENST00000647514
• ENSP00000493735

Symbol

• SDR19C1
• SDR19C1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
pathway	0.95
disease perturbation	0.9
histone modification site profile	0.76
cell type or tissue	0.72
tissue sample	0.68

Protein Classes

DTO Classes

Dehydrogenase/reductase Sdr Family Member 11

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.89   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 136   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.89   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 136   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0