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Tbio
CNDP1
Beta-Ala-His dipeptidase

Protein Summary
Description
This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358821
  • ENSP00000351682
  • ENSG00000150656

Symbol
  • CN1
  • CPGL2
  • CN1
  • CPGL2
  • HsT2308
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.74
gene perturbation
0.71
protein domain
0.58
disease
0.53
molecular function
0.49


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.49   (req: < 5)
Gene RIFs: 35   (req: <= 3)
Antibodies: 342   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 87.49   (req: >= 5)
Gene RIFs: 35   (req: > 3)
Antibodies: 342   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Pathways (6)
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Histidine metabolism
KEGG
Arginine and proline metabolism
KEGG
beta-Alanine metabolism
KEGG
Metabolic pathways
Name
Explore in Pharos
Explore in Source
Histidine metabolism
Arginine and proline metabolism
beta-Alanine metabolism
Metabolic pathways
Gene Ontology Terms (8)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (80)
1 – 10 of 80
POTEF
Tbio
Novelty: 0.01093698
p_int: 0.998227282
p_ni: 0.001772716
p_wrong: 1e-9
Data Source: BioPlex
CNDP2
Tbio
Family: Enzyme
Novelty: 0.00305222
p_int: 0.994151994
p_ni: 0.005848006
Score: 0.954
Data Source: BioPlex,STRINGDB
SLC16A10
Tbio
Family: Transporter
Novelty: 0.03767726
p_int: 0.972659725
p_ni: 0.021824044
p_wrong: 0.00551623
Score: 0.278
Data Source: BioPlex,STRINGDB
RAB3B
Tbio
Family: Enzyme
Novelty: 0.03851756
p_int: 0.961197419
p_ni: 0.01501117
p_wrong: 0.023791411
Score: 0.186
Data Source: BioPlex,STRINGDB
MANEA
Tbio
Family: Enzyme
Novelty: 0.03417339
p_int: 0.929812105
p_ni: 0.07018788
p_wrong: 1.5e-8
Score: 0.186
Data Source: BioPlex,STRINGDB
ESR1
Tclin
Family: NR
Novelty: 0.00008166
p_int: 0.901555575
p_ni: 0.098441636
p_wrong: 0.00000279
Score: 0.194
Data Source: BioPlex,STRINGDB
SLC25A16
Tbio
Family: Transporter
Novelty: 0.00123354
p_int: 0.900779885
p_ni: 0.099190843
p_wrong: 0.000029273
Score: 0.167
Data Source: BioPlex,STRINGDB
HSP90AB4P
Tdark
p_int: 0.848856318
p_ni: 0.151143682
Data Source: BioPlex
COX7A2
Tbio
Family: Enzyme
Novelty: 0.05966072
p_int: 0.804102899
p_ni: 0.195626906
p_wrong: 0.000270194
Score: 0.232
Data Source: BioPlex,STRINGDB
PIGM
Tbio
Family: Enzyme
Novelty: 0.02562642
p_int: 0.779579445
p_ni: 0.21979261
p_wrong: 0.000627945
Score: 0.212
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  87.49

PubMed score by year
PubTator Score  79.77

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer