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Tbio
ZNF512B
Zinc finger protein 512B

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369888
  • ENSP00000358904
  • ENSG00000196700

Symbol
  • KIAA1196
  • GM632
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.68
interacting protein
0.64
cell line
0.57
microRNA
0.57
hub protein
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.55   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.55   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
2
3
88
BMI-adjusted waist-hip ratio
2
4
4
83.5
mean reticulocyte volume
1
1
1
79
alkaline phosphatase measurement
2
3
2
6.2
75.5
low density lipoprotein cholesterol measurement
2
1
2
70.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
3
88
BMI-adjusted waist-hip ratio
4
83.5
mean reticulocyte volume
1
79
alkaline phosphatase measurement
2
6.2
75.5
low density lipoprotein cholesterol measurement
2
70.9
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 512B
719372
Rat
RGD:1305284
311721
Dog
zinc finger protein 512B
VGNC:48744
485983
Horse
zinc finger protein 512B
VGNC:25334
100147562
Anole lizard
zinc finger protein 512B
100557363
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zinc finger protein 512B
Rat
Dog
zinc finger protein 512B
Horse
zinc finger protein 512B
Anole lizard
zinc finger protein 512B
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q96KM6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Protein-Protein Interactions (31)
1 – 10 of 31
RBBP7
Tbio
Novelty:  0.01795364
p_int:  0.999999954
p_ni:  4.3e-8
p_wrong:  3e-9
Score:  0.729
Data Source:  BioPlex,STRINGDB
FHL3
Tbio
Novelty:  0.11505924
p_int:  0.999999775
p_ni:  2.25e-7
Score:  0.208
Data Source:  BioPlex,STRINGDB
HDAC1
Tclin
Family:  Epigenetic
Novelty:  0.00065244
p_int:  0.970311813
p_ni:  0.002804071
p_wrong:  0.026884116
Score:  0.582
Data Source:  BioPlex,STRINGDB
MTA1
Tbio
Family:  TF
Novelty:  0.00464618
p_int:  0.926362855
p_ni:  0.001119715
p_wrong:  0.07251743
Score:  0.844
Data Source:  BioPlex,STRINGDB
RADX
Tdark
Novelty:  0.0935142
Score:  0.632
Data Source:  STRINGDB
RPL37
Tbio
Novelty:  0.03935854
Score:  0.628
Data Source:  STRINGDB
INTS8
Tdark
Novelty:  0.03933008
Score:  0.607
Data Source:  STRINGDB
ZFC3H1
Tbio
Novelty:  0.17313739
Score:  0.573
Data Source:  STRINGDB
PPP2R5A
Tchem
Family:  Enzyme
Novelty:  0.03073487
Score:  0.557
Data Source:  STRINGDB
EMC7
Tdark
Novelty:  0.28771768
Score:  0.557
Data Source:  STRINGDB
Publication Statistics
PubMed Score  10.55

PubMed score by year
PubTator Score  8.42

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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