Tbio BTBD6 BTB/POZ domain-containing protein 6

Protein Summary

Description

Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity). Involved in late neuronal development and muscle formation (By similarity).

Uniprot Accession IDs

• Q96KE9
• Q8IVQ7
• Q9BR94

Gene Name

• BTBD6

Ensembl ID

• ENST00000327471
• ENSP00000329361
• ENSG00000184887
• ENST00000392554
• ENSP00000376337
• ENST00000463376
• ENSP00000418150
• ENST00000536364
• ENSP00000443091

Symbol

• BDPL
• BDPL

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.83
protein domain	0.73
kinase perturbation	0.71
tissue sample	0.68
cell type or tissue	0.67

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.95   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 145   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.95   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0