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Tbio
ZC3H10
Zinc finger CCCH domain-containing protein 10

Protein Summary
Description
Specific regulator of miRNA biogenesis. Binds, via the C3H1-type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000257940
  • ENSP00000257940
  • ENSG00000135482

Symbol
  • ZC3HDC10
  • ZC3HDC10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.97
histone modification site profile
0.77
transcription factor
0.68
kinase perturbation
0.66
disease perturbation
0.62


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.49   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 121   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.49   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 121   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 10
VGNC:14420
451982
Macaque
zinc finger CCCH-type containing 10
711633
Mouse
MGI:2143670
103284
Rat
RGD:1587846
685928
Dog
zinc finger CCCH-type containing 10
VGNC:48550
481106
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger CCCH-type containing 10
Macaque
zinc finger CCCH-type containing 10
Mouse
Rat
Dog
zinc finger CCCH-type containing 10
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96K80-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (9)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (49)
1 – 10 of 49
MLLT6
Tdark
Family: Epigenetic
Novelty: 0.03728427
p_int: 0.999989573
p_ni: 0.000010425
p_wrong: 2e-9
Score: 0.189
Data Source: BioPlex,STRINGDB
CEBPG
Tbio
Family: TF
Novelty: 0.07956633
p_int: 0.986349956
p_ni: 0.012637775
p_wrong: 0.001012269
Data Source: BioPlex
RPL37A
Tbio
Novelty: 0.03475061
p_int: 0.979565224
p_ni: 0.019983504
p_wrong: 0.000451272
Score: 0.517
Data Source: BioPlex,STRINGDB
RPL30
Tbio
Novelty: 0.0134194
p_int: 0.95644776
p_ni: 0.043040936
p_wrong: 0.000511304
Score: 0.392
Data Source: BioPlex,STRINGDB
RPL18
Tbio
Novelty: 0.01765545
p_int: 0.956315868
p_ni: 0.043603672
p_wrong: 0.000080461
Score: 0.416
Data Source: BioPlex,STRINGDB
RPL7A
Tbio
Novelty: 0.01674027
p_int: 0.792526162
p_ni: 0.117665817
p_wrong: 0.089808021
Data Source: BioPlex
ESYT1
Tbio
Novelty: 0.03069611
Score: 0.851
Data Source: STRINGDB
BCDIN3D
Tbio
Family: Enzyme
Novelty: 0.1619174
Score: 0.77
Data Source: STRINGDB
NFYA
Tbio
Family: TF
Novelty: 0.00507094
Score: 0.723
Data Source: STRINGDB
ZC3H4
Tbio
Novelty: 0.14897433
Score: 0.683
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.49

PubMed score by year
PubTator Score  1.6

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer