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Tbio
SLC45A3
Solute carrier family 45 member 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367145
  • ENSP00000356113
  • ENSG00000158715

Symbol
  • PCANAP6
  • PRST
  • PRST
  • IPCA6
  • IPCA-2
  • IPCA-6
  • IPCA-8
  • PCANAP2
  • PCANAP6
  • PCANAP8
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.83
transcription factor
0.79
transcription factor perturbation
0.74
PubMedID
0.6
tissue sample
0.6


Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.51   (req: < 5)
Gene RIFs: 15   (req: <= 3)
Antibodies: 188   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.51   (req: >= 5)
Gene RIFs: 15   (req: > 3)
Antibodies: 188   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
prostate specific antigen measurement
5
6
6
90.6
basophil count
3
3
3
89.6
appendicular lean mass
2
1
2
80.5
4
2
1
1.1
79.1
monocyte percentage of leukocytes
2
2
2
74.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
prostate specific antigen measurement
6
90.6
basophil count
3
89.6
appendicular lean mass
2
80.5
1
1.1
79.1
monocyte percentage of leukocytes
2
74.3
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 45 member 3
VGNC:6123
457672
Macaque
solute carrier family 45 member 3
697420
Mouse
MGI:1922082
212980
Rat
RGD:1309764
304785
Dog
solute carrier family 45 member 3
VGNC:46424
488575
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 45 member 3
Macaque
solute carrier family 45 member 3
Mouse
Rat
Dog
solute carrier family 45 member 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96JT2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (5)
Cellular hexose transport (R-HSA-189200)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cellular hexose transport
Reactome
SLC-mediated transmembrane transport
Reactome
Transport of small molecules
Name
Explore in Pharos
Explore in Source
Cellular hexose transport
SLC-mediated transmembrane transport
Transport of small molecules
Protein-Protein Interactions (56)
1 – 10 of 56
TMPRSS2
Tchem
Family:  Enzyme
Novelty:  0.00117884
Score:  0.774
Data Source:  STRINGDB
NUCKS1
Tbio
Family:  Enzyme
Novelty:  0.02654614
Score:  0.768
Data Source:  STRINGDB
ELK4
Tbio
Family:  TF
Novelty:  0.03211949
Score:  0.732
Data Source:  STRINGDB
PM20D1
Tdark
Family:  Enzyme
Novelty:  0.07205788
Score:  0.725
Data Source:  STRINGDB
CANT1
Tbio
Family:  Enzyme
Novelty:  0.02640333
Score:  0.714
Data Source:  STRINGDB
ACPP
Tchem
Family:  Enzyme
Novelty:  0.00364265
Score:  0.712
Data Source:  STRINGDB
ETV1
Tbio
Family:  TF
Novelty:  0.0055085
Score:  0.675
Data Source:  STRINGDB
ETV5
Tbio
Family:  TF
Novelty:  0.00052506
Score:  0.651
Data Source:  STRINGDB
ETV4
Tbio
Family:  TF
Novelty:  0.00317361
Score:  0.651
Data Source:  STRINGDB
TMEM79
Tbio
Novelty:  0.0624393
Score:  0.647
Data Source:  STRINGDB
Publication Statistics
PubMed Score  51.51

PubMed score by year
PubTator Score  26.81

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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