RADIL
Ras-associating and dilute domain-containing protein
Protein Summary
Downstream effector of Rap required for cell adhesion and migration of neural crest precursors during development.
- ENST00000399583
- ENSP00000382492
- ENSG00000157927
- KIAA1849
- RASIP2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.92 | ||
cell type or tissue | 0.69 | ||
gene perturbation | 0.65 | ||
transcription factor binding site profile | 0.62 | ||
transcription factor | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.79 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 137 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 6.79 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 137 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (30)
FLRT1
Novelty: 0.23047852
p_int: 0.999957918
p_ni: 0.000041995
p_wrong: 8.7e-8
Score: 0.249
Data Source: BioPlex,STRINGDB
PNKD
Family: Enzyme
Novelty: 0.02456078
p_int: 0.99991259
p_ni: 0.000087377
p_wrong: 3.2e-8
Data Source: BioPlex
DEF8
Novelty: 0.21146806
p_int: 0.99966657
p_ni: 0.000333428
p_wrong: 2e-9
Score: 0.2
Data Source: BioPlex,STRINGDB
CD83
Novelty: 0.00138653
p_int: 0.997491915
p_ni: 0.002439402
p_wrong: 0.000068683
Data Source: BioPlex
EFNB2
Novelty: 0.00255095
p_int: 0.792573993
p_ni: 0.000826822
p_wrong: 0.206599184
Score: 0.165
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (5)
Components (2)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (4)
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
mosquito bite reaction itch intensity measurement | 1 | 1 | 1 | 24.5 | |||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 21.5 | |||||
parental longevity | 1 | 1 | 1 | 17.8 | |||||
electrocardiography | 1 | 1 | 1 | 15.8 | |||||
Items per page:
1 – 4 of 4
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
mosquito bite reaction itch intensity measurement | 1 | 24.5 | |||||
apolipoprotein A 1 measurement | 1 | 21.5 | |||||
parental longevity | 1 | 17.8 | |||||
electrocardiography | 1 | 15.8 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | Rap associating with DIL domain | VGNC:8743 | 463241 | |||||
Macaque | Rap associating with DIL domain | 700979 | ||||||
Mouse | MGI:2443088 | 231858 | ||||||
Rat | RGD:1306155 | 304299 | ||||||
Horse | Rap associating with DIL domain | VGNC:22152 | 100060713 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | Rap associating with DIL domain | |||||
Macaque | Rap associating with DIL domain | |||||
Mouse | ||||||
Rat | ||||||
Horse | Rap associating with DIL domain | |||||
Publication Statistics
PubMed Score 6.79
PubMed score by year
PubTator Score 0.56
PubTator score by year
Related Publications
Text Mined References (18)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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