RSRC1
Serine/Arginine-related protein 53
Protein Summary
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
- ENST00000295930
- ENSP00000295930
- ENSG00000174891
- ENST00000312179
- ENSP00000308671
- ENST00000464171
- ENSP00000419794
- ENST00000480820
- ENSP00000420150
- ENST00000611884
- ENSP00000481697
- SRRP53
- BM-011
- SFRS21
- SRrp53
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.88 | ||
kinase perturbation | 0.84 | ||
transcription factor binding site profile | 0.74 | ||
transcription factor perturbation | 0.74 | ||
histone modification site profile | 0.67 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.8 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 73 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 8.8 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 73 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0