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Tdark
ZNF496
Zinc finger protein 496

Protein Summary
Description
DNA-binding transcription factor that can both act as an activator and a repressor.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294753
  • ENSP00000294753
  • ENSG00000162714

Symbol
  • ZKSCAN17
  • NIZP1
  • ZFP496
  • ZSCAN49
  • ZKSCAN17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
kinase perturbation
0.81
histone modification site profile
0.73
transcription factor binding site profile
0.72
cell line
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.84   (req: < 5)
View Publications
Gene RIFs: 1   (req: <= 3)
View Gene RIFs
Antibodies: 135   (req: <= 50)
View Antibodies
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.84   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 135   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
View GO Terms
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
1452 targets
R-HSA-74160
Reactome
Generic Transcription Pathway
1195 targets
R-HSA-212436
Reactome
RNA Polymerase II Transcription
1314 targets
R-HSA-73857
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
1452 targets
R-HSA-74160
Generic Transcription Pathway
1195 targets
R-HSA-212436
RNA Polymerase II Transcription
1314 targets
R-HSA-73857
Protein-Protein Interactions (36)
1 – 10 of 36
ZNF232
Tdark
Family: TF
Novelty: 0.91666667
p_int: 0.999802742
p_ni: 0.000197206
p_wrong: 5.2e-8
Data Source: BioPlex
ZNF397
Tbio
Family: TF
Novelty: 0.86610879
p_int: 0.999784389
p_ni: 0.000215329
p_wrong: 2.81e-7
Data Source: BioPlex
GTF3C2
Tdark
Novelty: 0.29005525
p_int: 0.999580813
p_ni: 0.000418856
p_wrong: 3.32e-7
Score: 0.557
Data Source: BioPlex,STRINGDB
XAGE1A
Tbio
Novelty: 0.04709514
p_int: 0.99926839
p_ni: 0.00073159
p_wrong: 2e-8
Data Source: BioPlex
CSNK2B
Tbio
Family: Kinase
Novelty: 0.00171173
p_int: 0.99918176
p_ni: 0.000811162
p_wrong: 0.000007078
Data Source: BioPlex
PRM2
Tbio
Novelty: 0.00641454
p_int: 0.998485819
p_ni: 0.001508205
p_wrong: 0.000005976
Data Source: BioPlex
PPAN
Tbio
Novelty: 0.0010549
p_int: 0.998425197
p_ni: 0.001571226
p_wrong: 0.000003576
Data Source: BioPlex
ZSCAN1
Tbio
Family: TF
Novelty: 0.03466459
p_int: 0.998255863
p_ni: 0.000255809
p_wrong: 0.001488328
Score: 0.205
Data Source: BioPlex,STRINGDB
FOXD4L6
Tdark
Family: TF
Novelty: 3
p_int: 0.997770203
p_ni: 0.00222691
p_wrong: 0.000002887
Score: 0.234
Data Source: BioPlex,STRINGDB
FBL
Tbio
Family: Enzyme
Novelty: 0.00044932
p_int: 0.997685449
p_ni: 0.000169345
p_wrong: 0.002145206
Score: 0.51
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  4.84

PubMed score by year
PubTator Score  4.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer