Tbio ZNF496 Zinc finger protein 496

Protein Summary

Description

DNA-binding transcription factor that can both act as an activator and a repressor.

Uniprot Accession IDs

• Q96IT1
• Q8TBS2

Gene Name

• ZNF496

Ensembl ID

• ENST00000294753
• ENSP00000294753
• ENSG00000162714

Symbol

• ZKSCAN17
• NIZP1
• ZFP496
• ZSCAN49
• ZKSCAN17

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
kinase perturbation	0.81
histone modification site profile	0.73
transcription factor binding site profile	0.72
cell line	0.64

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.6   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 135   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.6   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 135   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0