Tbio TENT5A Terminal nucleotidyltransferase 5A

Protein Summary

Description

Probable nucleotidyltransferase that may act as a non-canonical poly(A) RNA polymerase.

Uniprot Accession IDs

• Q96IP4
• A8K7U4
• Q5TF86
• Q8NFZ9
• Q9BW32
• Q9NXV5

Gene Name

• TENT5A

Ensembl ID

• ENST00000320172
• ENSP00000318298
• ENSG00000112773
• ENST00000369754
• ENSP00000358769

Symbol

• C6orf37
• FAM46A
• XTP11
• OI18
• XTP11
• FAM46A
• C6orf37

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	1
microRNA	0.83
transcription factor binding site profile	0.81
gene perturbation	0.76
histone modification site profile	0.76

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.77   (req: < 5)

Gene RIFs: 14   (req: <= 3)

Antibodies: 101   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.77   (req: >= 5)

Gene RIFs: 14   (req: > 3)

Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0