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Tdark
TMEM41A
Transmembrane protein 41A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000421852
  • ENSP00000406885
  • ENSG00000163900

Symbol
  • 2900010K02Rik
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.96
transcription factor perturbation
0.8
transcription factor binding site profile
0.78
histone modification site profile
0.7
tissue sample
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.11   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 59   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.11   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 59   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
2
2
3
40.4
glomerular filtration rate
1
1
1
33
sex hormone-binding globulin measurement
2
1
2
13.4
urate measurement
1
1
1
7.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
3
40.4
glomerular filtration rate
1
33
sex hormone-binding globulin measurement
2
13.4
urate measurement
1
7.2
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 41A
VGNC:2613
471028
Macaque
transmembrane protein 41A
700975
Mouse
MGI:1913914
66664
Rat
RGD:1591692
681708
Dog
transmembrane protein 41A
VGNC:47579
488111
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 41A
Macaque
transmembrane protein 41A
Mouse
Rat
Dog
transmembrane protein 41A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96HV5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (18)
1 – 10 of 18
VIPR2
Tchem
Family:  GPCR
Novelty:  0.00463802
p_int:  0.860061896
p_ni:  0.000100998
p_wrong:  0.139837106
Score:  0.189
Data Source:  BioPlex,STRINGDB
TMEM199
Tbio
Novelty:  0.05799147
Score:  0.717
Data Source:  STRINGDB
CYBC1
Tdark
Novelty:  0.72567331
Score:  0.715
Data Source:  STRINGDB
SEC11C
Tdark
Family:  Enzyme
Novelty:  0.19577003
Score:  0.66
Data Source:  STRINGDB
TMEM109
Tbio
Novelty:  0.2414463
Score:  0.636
Data Source:  STRINGDB
ERG
Tbio
Family:  TF
Novelty:  0.04049734
Score:  0.635
Data Source:  STRINGDB
TMEM126A
Tbio
Novelty:  0.11759225
Score:  0.613
Data Source:  STRINGDB
TAPBPL
Tbio
Novelty:  0.06343547
Score:  0.605
Data Source:  STRINGDB
METTL7A
Tbio
Family:  Enzyme
Novelty:  0.10143651
Score:  0.597
Data Source:  STRINGDB
MAP3K13
Tchem
Family:  Kinase
Novelty:  0.00461563
Score:  0.583
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.11

PubMed score by year
PubTator Score  0.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer