PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 0.99 | ||
histone modification site profile | 0.88 | ||
molecular function | 0.76 | ||
cellular component | 0.73 | ||
hub protein | 0.67 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Autophagy | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Macroautophagy | ||||
Reactome | Mitophagy | ||||
Reactome | Receptor Mediated Mitophagy | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Autophagy | ||||
Cellular responses to external stimuli | ||||
Macroautophagy | ||||
Mitophagy | ||||
Receptor Mediated Mitophagy | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | CACAO | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 2 | 2 | 2 | 55.8 | |||||
reticulocyte measurement | 1 | 1 | 1 | 52.7 | |||||
smoking status measurement | 2 | 1 | 2 | 51.4 | |||||
mean corpuscular volume | 1 | 1 | 1 | 48.5 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 2 | 55.8 | |||||
reticulocyte measurement | 1 | 52.7 | |||||
smoking status measurement | 2 | 51.4 | |||||
mean corpuscular volume | 1 | 48.5 | |||||
mean reticulocyte volume | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | VGNC:8491 | 452388 | |||||
Macaque | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | 693782 | ||||||
Mouse | MGI:1919792 | 72542 | ||||||
Rat | RGD:1312028 | 288731 | ||||||
Dog | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | VGNC:52956 | 486221 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | |||||
Macaque | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | |||||
Mouse | ||||||
Rat | ||||||
Dog | PGAM family member 5, mitochondrial serine/threonine protein phosphatase | |||||
PMID | Year | Title |
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