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Tbio
CCDC34
Coiled-coil domain-containing protein 34

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.2   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.2   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
2
2
93.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
93.8
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 34
VGNC:3171
451087
Macaque
coiled-coil domain containing 34
699208
Mouse
MGI:1915451
68201
Rat
RGD:1560583
362187
Horse
coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 34
Macaque
coiled-coil domain containing 34
Mouse
Rat
Horse
coiled-coil domain containing 34 [Source:HGNC Symbol;Acc:HGNC:25079]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96HJ3-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (31)
1 – 10 of 31
RABL2A
Tbio
Family: Enzyme
Novelty: 0.09940618
p_int: 0.999999821
p_ni: 1.78e-7
p_wrong: 1e-9
Score: 0.519
Data Source: BioPlex,STRINGDB
ACTBL2
Tbio
Novelty: 0.18080702
p_int: 0.953903764
p_ni: 0.046096236
Data Source: BioPlex
FAM216A
Tdark
Novelty: 0.74863593
Score: 0.713
Data Source: STRINGDB
CCDC134
Tbio
Novelty: 0.24073583
Score: 0.667
Data Source: STRINGDB
FAM198B
Tbio
Novelty: 0.16692868
Score: 0.639
Data Source: STRINGDB
DEUP1
Tbio
Novelty: 0.13274391
Score: 0.634
Data Source: STRINGDB
LIN7C
Tbio
Novelty: 0.06778878
Score: 0.615
Data Source: STRINGDB
LGR4
Tbio
Family: GPCR
Novelty: 0.01180123
Score: 0.589
Data Source: STRINGDB
GINS2
Tbio
Novelty: 0.0078966
Score: 0.558
Data Source: STRINGDB
SLMAP
Tbio
Novelty: 0.03974856
Score: 0.544
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.20

PubMed score by year
PubTator Score  1.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer