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Tdark
GRAMD2B
GRAM domain-containing protein 2B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000285689
  • ENSP00000285689
  • ENSG00000155324
  • ENST00000511134
  • ENSP00000426088
  • ENST00000513040
  • ENSP00000426120
  • ENST00000542322
  • ENSP00000441876
  • ENST00000544396
  • ENSP00000444049

Symbol
  • GRAMD3
  • NS3TP2
  • GRAMD3
  • NS3TP2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 203   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.68   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 203   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (40)
1 – 10 of 40
EFCAB14
Tdark
Novelty:  1.84099333
p_int:  1
Score:  0.403
Data Source:  BioPlex,STRINGDB
GRAMD1C
Tdark
Novelty:  0.46102163
p_int:  0.999999669
p_ni:  3.09e-7
p_wrong:  2.2e-8
Score:  0.783
Data Source:  BioPlex,STRINGDB
GRAMD1B
Tbio
Novelty:  0.2994102
p_int:  0.999999631
p_ni:  3.67e-7
p_wrong:  2e-9
Score:  0.69
Data Source:  BioPlex,STRINGDB
CASC4
Tbio
Novelty:  0.05791147
p_int:  0.999982944
p_ni:  0.00001704
p_wrong:  1.6e-8
Score:  0.252
Data Source:  BioPlex,STRINGDB
EXD2
Tbio
Family:  Enzyme
Novelty:  0.09804411
p_int:  0.999934441
p_ni:  0.000065559
Score:  0.201
Data Source:  BioPlex,STRINGDB
GRAMD1A
Tbio
Novelty:  0.15461113
p_int:  0.999911604
p_ni:  0.000088396
Score:  0.386
Data Source:  BioPlex,STRINGDB
GOLM1
Tbio
Novelty:  0.00752112
p_int:  0.999039509
p_ni:  0.000960491
Score:  0.183
Data Source:  BioPlex,STRINGDB
TXNDC15
Tdark
Novelty:  0.23488442
p_int:  0.998031544
p_ni:  0.001968455
Data Source:  BioPlex
TXLNG
Tbio
Novelty:  0.08274423
p_int:  0.997996781
p_ni:  0.002003217
p_wrong:  1e-9
Score:  0.524
Data Source:  BioPlex,STRINGDB
MARCH5
Tbio
Family:  Epigenetic
Novelty:  0.02702094
p_int:  0.988219899
p_ni:  3.6e-7
p_wrong:  0.011779741
Score:  0.243
Data Source:  BioPlex,STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
IntAct
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
2
2
2
45.7
1
1
0
1.9
33.1
1
1
0
2.3
33.1
1
1
0
1.9
33.1
hemoglobin measurement
1
1
1
4.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
2
45.7
0
1.9
33.1
0
2.3
33.1
0
1.9
33.1
hemoglobin measurement
1
4.9
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
GRAM domain containing 2B
702639
Mouse
MGI:1914815
107022
Rat
RGD:1311016
307288
Dog
GRAM domain containing 2B
VGNC:41469
474662
Opossum
GRAM domain containing 2B
100618417
Species
Name
OMA
EggNOG
Inparanoid
Macaque
GRAM domain containing 2B
Mouse
Rat
Dog
GRAM domain containing 2B
Opossum
GRAM domain containing 2B
Publication Statistics
PubMed Score 1.68
PubMed score by year
PubTator Score 0.72
PubTator score by year