PLPPR2
Phospholipid phosphatase-related protein type 2
Protein Summary
- ENST00000251473
- ENSP00000251473
- ENSG00000105520
- ENST00000591608
- ENSP00000466898
- LPPR2
- PRG4
- PRG4
- LPPR2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.13 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 87 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.13 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 87 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (52)
C9orf40
Novelty: 2.72763898
p_int: 0.999932539
p_ni: 0.000067458
p_wrong: 3e-9
Score: 0.189
Data Source: BioPlex,STRINGDB
DPP9
Family: Enzyme
Novelty: 0.00976924
p_int: 0.997569996
p_ni: 0.002430003
Data Source: BioPlex
EPN1
Novelty: 0.01788784
p_int: 0.989005207
p_ni: 0.010994729
p_wrong: 6.4e-8
Score: 0.198
Data Source: BioPlex,STRINGDB
METAP1
Family: Enzyme
Novelty: 0.01816253
p_int: 0.983109264
p_ni: 0.016890736
Score: 0.161
Data Source: BioPlex,STRINGDB
SEC24D
Novelty: 0.04795527
p_int: 0.971423947
p_ni: 0.028236365
p_wrong: 0.000339688
Score: 0.218
Data Source: BioPlex,STRINGDB
METAP2
Family: Enzyme
Novelty: 0.00570955
p_int: 0.956756419
p_ni: 0.043243581
Data Source: BioPlex
Nearest Tclin Targets
Pathways (6)
Reactome (5)
PathwayCommons (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | GPCR ligand binding | ||||
Reactome | Lysosphingolipid and LPA receptors | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Class A/1 (Rhodopsin-like receptors) | ||||
GPCR ligand binding | ||||
Lysosphingolipid and LPA receptors | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Functions (3)
Components (1)
Processes (2)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations ()
GWAS Traits (14)
Items per page:
1 – 5 of 14
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
total cholesterol measurement | 2 | 2 | 2 | 80.2 | |||||
diastolic blood pressure | 1 | 1 | 1 | 78.6 | |||||
Agents acting on the renin-angiotensin system use measurement | 1 | 1 | 1 | 76.5 | |||||
3 | 1 | 1 | 7.8 | 65.4 | |||||
Calcium channel blocker use measurement | 1 | 1 | 1 | 64.9 | |||||
Items per page:
1 – 5 of 14
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
total cholesterol measurement | 2 | 80.2 | |||||
diastolic blood pressure | 1 | 78.6 | |||||
Agents acting on the renin-angiotensin system use measurement | 1 | 76.5 | |||||
1 | 7.8 | 65.4 | |||||
Calcium channel blocker use measurement | 1 | 64.9 | |||||
Find similar targets by:
IDG Resources
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Macaque | phospholipid phosphatase related 2 | 714388 | ||||||
Mouse | MGI:2384575 | 235044 | ||||||
Rat | RGD:1597171 | 300443 | ||||||
Dog | phospholipid phosphatase related 2 | 484944 | ||||||
Horse | phospholipid phosphatase related 2 | 100057105 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Macaque | phospholipid phosphatase related 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | phospholipid phosphatase related 2 | |||||
Horse | phospholipid phosphatase related 2 | |||||
Publication Statistics
PubMed Score 1.13
PubMed score by year
PubTator Score 0.59
PubTator score by year
Related Publications
Text Mined References (6)
Items per page:
0 of 0
PMID | Year | Title |
|---|