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Tdark
FAM89A
Protein FAM89A

Protein Classes
Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000366654
  • ENSP00000355614
  • ENSG00000182118

Symbol
  • C1orf153
  • C1orf153
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.9
histone modification site profile
0.74
transcription factor perturbation
0.61
cell type or tissue
0.6
microRNA
0.6


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 8   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 8   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
1
1
81.6
BMI-adjusted waist-hip ratio
1
1
1
81.5
hip circumference
1
1
1
79
BMI-adjusted hip circumference
1
1
1
60.5
hematocrit
1
1
1
60.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
waist-hip ratio
1
81.6
BMI-adjusted waist-hip ratio
1
81.5
hip circumference
1
79
BMI-adjusted hip circumference
1
60.5
hematocrit
1
60.2
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 89 member A
VGNC:10632
457816
Mouse
MGI:1916877
69627
Rat
RGD:1309879
361441
Dog
family with sequence similarity 89 member A
VGNC:50879
488974
Cow
family with sequence similarity 89 member A
VGNC:28842
616421
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 89 member A
Mouse
Rat
Dog
family with sequence similarity 89 member A
Cow
family with sequence similarity 89 member A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96GI7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (13)
1 – 10 of 13
UBXN2B
Tbio
Novelty:  0.67291382
p_int:  0.937892369
p_ni:  1e-8
p_wrong:  0.06210762
Score:  0.622
Data Source:  BioPlex,STRINGDB
GEMIN2
Tbio
Novelty:  0.02072868
Score:  0.557
Data Source:  STRINGDB
GFRA3
Tbio
Novelty:  0.10149548
Score:  0.553
Data Source:  STRINGDB
PURB
Tbio
Novelty:  0.02303518
Score:  0.55
Data Source:  STRINGDB
PTGIR
Tclin
Family:  GPCR
Novelty:  0.0091906
Score:  0.494
Data Source:  STRINGDB
ZFHX2
Tdark
Family:  TF
Novelty:  0.36674507
Score:  0.474
Data Source:  STRINGDB
FAM78A
Tdark
Novelty:  0.92171591
Score:  0.474
Data Source:  STRINGDB
PSPH
Tbio
Family:  Enzyme
Novelty:  0.01078634
Score:  0.473
Data Source:  STRINGDB
CLTA
Tbio
Novelty:  0.01900315
Score:  0.469
Data Source:  STRINGDB
RNF145
Tbio
Novelty:  0.30480192
Score:  0.455
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.76

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer