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Tbio
KLHDC7B
Kelch domain-containing protein 7B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000395676
  • ENSP00000379034
  • ENSG00000130487
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
tissue sample
0.6
cellular component
0.52
tissue
0.52
microRNA
0.39


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.43   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.43   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age-related hearing impairment
1
1
0
8.1
90.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age-related hearing impairment
0
8.1
90.2
Protein-Protein Interactions (16)
1 – 10 of 16
TRABD
Tdark
Novelty: 0.47132923
Score: 0.553
Data Source: STRINGDB
ODF3B
Tdark
Novelty: 0.2577355
Score: 0.541
Data Source: STRINGDB
ZFAND1
Tbio
Novelty: 0.59717262
Score: 0.539
Data Source: STRINGDB
DENND6B
Tbio
Novelty: 1.49514544
Score: 0.513
Data Source: STRINGDB
EVA1B
Tdark
Novelty: 2.1380272
Score: 0.504
Data Source: STRINGDB
RHBDF1
Tbio
Family: Enzyme
Novelty: 0.01942693
Score: 0.495
Data Source: STRINGDB
CYTH3
Tbio
Novelty: 0.00940752
Score: 0.456
Data Source: STRINGDB
LMF2
Tdark
Family: Enzyme
Novelty: 0.24810125
Score: 0.455
Data Source: STRINGDB
SH3D21
Tdark
Novelty: 0.79219583
Score: 0.44
Data Source: STRINGDB
GPR1
Tbio
Family: GPCR
Novelty: 0.01313419
Score: 0.436
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.43

PubMed score by year
PubTator Score  0.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer