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Tbio
PGM2
Phosphoglucomutase-2

Protein Summary
Description
Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000381967
  • ENSP00000371393
  • ENSG00000169299

Symbol
  • MSTP006
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
protein domain
0.92
transcription factor perturbation
0.91
histone modification site profile
0.89
tissue sample
0.75


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 110.23   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 110.23   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
1
2
83.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
2
83.2
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
phosphoglucomutase 2
VGNC:12953
461162
Macaque
phosphoglucomutase 2
100424648
Mouse
MGI:97564
66681
Dog
phosphoglucomutase 2
VGNC:44464
479116
Horse
phosphoglucomutase 2
VGNC:21358
100064893
Species
Name
OMA
EggNOG
Inparanoid
Chimp
phosphoglucomutase 2
Macaque
phosphoglucomutase 2
Mouse
Dog
phosphoglucomutase 2
Horse
phosphoglucomutase 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96G03-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (25)
Galactose catabolism (R-HSA-70370)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Galactose catabolism
Reactome
Glycogen breakdown (glycogenolysis)
Reactome
Glycogen metabolism
Reactome
Glycogen synthesis
Reactome
Immune System
Name
Explore in Pharos
Explore in Source
Galactose catabolism
Glycogen breakdown (glycogenolysis)
Glycogen metabolism
Glycogen synthesis
Immune System
Gene Ontology Terms (15)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Experiment (EXP)
Reactome
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (143)
1 – 10 of 143
PGM1
Tbio
Family:  Enzyme
Novelty:  0.00163947
Score:  0.997
Data Source:  STRINGDB
GPI
Tbio
Family:  Enzyme
Novelty:  0.00095404
Score:  0.971
Data Source:  STRINGDB
DERA
Tbio
Family:  Enzyme
Novelty:  0.0079635
Score:  0.968
Data Source:  STRINGDB
PNP
Tclin
Family:  Enzyme
Novelty:  0.0019084
Score:  0.964
Data Source:  STRINGDB
UGP2
Tbio
Family:  Enzyme
Novelty:  0.00760963
Score:  0.963
Data Source:  STRINGDB
TKT
Tchem
Family:  Enzyme
Novelty:  0.00333936
Score:  0.963
Data Source:  STRINGDB
RBKS
Tbio
Family:  Kinase
Novelty:  0.01660806
Score:  0.958
Data Source:  STRINGDB
RPIA
Tbio
Family:  Enzyme
Novelty:  0.00968705
Score:  0.949
Data Source:  STRINGDB
HK1
Tchem
Family:  Kinase
Novelty:  0.00195554
Score:  0.936
Data Source:  STRINGDB
PYGM
Tchem
Family:  Enzyme
Novelty:  0.00507768
Score:  0.93
Data Source:  STRINGDB
Publication Statistics
PubMed Score  110.23

PubMed score by year
PubTator Score  56.87

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer