OTUB1
Ubiquitin thioesterase OTUB1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.94 | ||
co-expressed gene | 0.82 | ||
transcription factor binding site profile | 0.77 | ||
biological process | 0.68 | ||
transcription factor | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Deubiquitination | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Ovarian tumor domain proteases | ||||
Reactome | Post-translational protein modification | ||||
Reactome | Ub-specific processing proteases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Deubiquitination | ||||
Metabolism of proteins | ||||
Ovarian tumor domain proteases | ||||
Post-translational protein modification | ||||
Ub-specific processing proteases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 3 | 8 | 10 | 96.1 | |||||
uric acid measurement | 1 | 2 | 2 | 95.5 | |||||
waist-hip ratio | 1 | 6 | 6 | 91.8 | |||||
urate measurement | 2 | 2 | 3 | 89.8 | |||||
BMI-adjusted waist circumference | 1 | 3 | 3 | 57.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 10 | 96.1 | |||||
uric acid measurement | 2 | 95.5 | |||||
waist-hip ratio | 6 | 91.8 | |||||
urate measurement | 3 | 89.8 | |||||
BMI-adjusted waist circumference | 3 | 57.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | OTU deubiquitinase, ubiquitin aldehyde binding 1 | VGNC:6538 | 742797 | |||||
Mouse | MGI:2147616 | 107260 | ||||||
Rat | RGD:1311329 | 293705 | ||||||
Dog | OTU deubiquitinase, ubiquitin aldehyde binding 1 | VGNC:49784 | 100855636 | |||||
Horse | OTU deubiquitinase, ubiquitin aldehyde binding 1 | VGNC:21086 | 100054829 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | OTU deubiquitinase, ubiquitin aldehyde binding 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | OTU deubiquitinase, ubiquitin aldehyde binding 1 | |||||
Horse | OTU deubiquitinase, ubiquitin aldehyde binding 1 | |||||
PMID | Year | Title |
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