Tbio PTCD3 Pentatricopeptide repeat domain-containing protein 3, mitochondrial

Protein Summary

Description

Mitochondrial RNA-binding protein that has a role in mitochondrial translation.

Uniprot Accession IDs

• Q96EY7
• A6NHD2
• D6W5M1
• Q597H0
• Q658Y9
• Q9BUZ8
• Q9NWL0

Gene Name

• PTCD3

Ensembl ID

• ENST00000254630
• ENSP00000254630
• ENSG00000132300

Symbol

• MRPS39
• MRP-S39

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.97
kinase perturbation	0.97
histone modification site profile	0.9
cell type or tissue	0.86
disease perturbation	0.79

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.44   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 55   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.44   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 55   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0