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Tbio
HSPBAP1
HSPB1-associated protein 1

Protein Summary
Description
May play a role in cellular stress response. This gene encodes a protein that binds to one of the small heat shock proteins, specifically hsp27. Hsp27 is involved with cell growth and differentiation. This encoded protein was found to be abnormally expressed in patients with intractable epilepsy, although how brain function is affected remains unknown. [provided by RefSeq, Sep 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306103
  • ENSP00000302562
  • ENSG00000169087

Symbol
  • PASS1
  • PASS1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.83
kinase perturbation
0.76
transcription factor
0.75
tissue sample
0.7
cell type or tissue
0.69


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.68   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 210   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.68   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 210   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
HSPB1 associated protein 1
VGNC:7069
460635
Macaque
HSPB1 associated protein 1
715073
Mouse
MGI:1913917
66667
Rat
RGD:620870
171460
Dog
HSPB1 associated protein 1
VGNC:41819
478587
Species
Name
OMA
EggNOG
Inparanoid
Chimp
HSPB1 associated protein 1
Macaque
HSPB1 associated protein 1
Mouse
Rat
Dog
HSPB1 associated protein 1
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (33)
1 – 10 of 33
MAGEA1
Tbio
Novelty: 0.00506874
p_int: 0.99999999
p_ni: 5e-9
p_wrong: 5e-9
Score: 0.189
Data Source: BioPlex,STRINGDB
FOXD4L6
Tdark
Family: TF
Novelty: 9.78461538
p_int: 0.999999961
p_ni: 3.4e-8
p_wrong: 5e-9
Score: 0.209
Data Source: BioPlex,STRINGDB
NCALD
Tbio
Novelty: 0.03665351
p_int: 0.87818211
p_ni: 0.121467594
p_wrong: 0.000350296
Score: 0.305
Data Source: BioPlex,STRINGDB
HSPB1
Tchem
Novelty: 0.00081373
Score: 0.832
Data Source: STRINGDB
HSPB2
Tbio
Novelty: 0.00103909
Score: 0.816
Data Source: STRINGDB
JMJD4
Tbio
Novelty: 0.09951585
Score: 0.805
Data Source: STRINGDB
RIOX1
Tbio
Family: Epigenetic
Novelty: 0.06360414
Score: 0.805
Data Source: STRINGDB
HSPB3
Tbio
Novelty: 0.00078884
Score: 0.767
Data Source: STRINGDB
OGFOD2
Tdark
Family: Enzyme
Novelty: 0.70711512
Score: 0.743
Data Source: STRINGDB
MARK1
Tchem
Family: Kinase
Novelty: 0.02342173
Score: 0.662
Data Source: STRINGDB
Publication Statistics
PubMed Score  30.68

PubMed score by year
PubTator Score  17.45

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer