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Tdark
KTI12
Protein KTI12 homolog

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371614
  • ENSP00000360676
  • ENSG00000198841

Symbol
  • TOT4
  • SBBI81
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.84
molecular function
0.76
interacting protein
0.75
tissue
0.61
histone modification site profile
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.54   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 49   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.54   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (27)
1 – 10 of 27
GPR35
Tchem
Family:  GPCR
Novelty:  0.01188578
p_int:  0.949330827
p_ni:  7.1e-8
p_wrong:  0.050669103
Score:  0.689
Data Source:  BioPlex,STRINGDB
ELP3
Tbio
Family:  Epigenetic
Novelty:  0.0166061
Score:  0.914
Data Source:  STRINGDB
ELP1
Tbio
Novelty:  0.0035777
Score:  0.885
Data Source:  STRINGDB
ELP4
Tbio
Novelty:  0.03734233
Score:  0.876
Data Source:  STRINGDB
ELP2
Tbio
Novelty:  0.03034629
Score:  0.855
Data Source:  STRINGDB
DPH3
Tdark
Novelty:  0.05288317
Score:  0.839
Data Source:  STRINGDB
MOCS3
Tbio
Family:  Enzyme
Novelty:  0.039209
Score:  0.832
Data Source:  STRINGDB
URM1
Tbio
Novelty:  0.02579093
Score:  0.821
Data Source:  STRINGDB
CTU1
Tbio
Novelty:  0.04670058
Score:  0.789
Data Source:  STRINGDB
ALKBH8
Tbio
Novelty:  0.02797162
Score:  0.741
Data Source:  STRINGDB
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
59
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
59
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
KTI12 chromatin associated homolog
712824
Mouse
MGI:1923547
100087
Dog
KTI12 chromatin associated homolog
VGNC:42549
100688398
Xenopus
KTI12 chromatin associated homolog
XB-GENE-5813863
549045
Zebrafish
ZDB-GENE-060825-174
751662
Species
Name
OMA
EggNOG
Inparanoid
Macaque
KTI12 chromatin associated homolog
Mouse
Dog
KTI12 chromatin associated homolog
Xenopus
KTI12 chromatin associated homolog
Zebrafish
Publication Statistics
PubMed Score 12.54
PubMed score by year
PubTator Score 3.17
PubTator score by year