FAM120B
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.98 | ||
kinase perturbation | 0.88 | ||
histone modification site profile | 0.78 | ||
transcription factor binding site profile | 0.74 | ||
tissue sample | 0.63 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Developmental Biology | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | PPARA activates gene expression | ||||
Reactome | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Developmental Biology | ||||
Metabolism | ||||
Metabolism of lipids | ||||
PPARA activates gene expression | ||||
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
monocyte count | 1 | 1 | 1 | 72.6 | |||||
platelet crit | 1 | 1 | 1 | 72.2 | |||||
lymphocyte count | 2 | 2 | 2 | 72.1 | |||||
daytime rest measurement | 1 | 1 | 1 | 51.4 | |||||
hematocrit | 2 | 2 | 2 | 48.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
monocyte count | 1 | 72.6 | |||||
platelet crit | 1 | 72.2 | |||||
lymphocyte count | 2 | 72.1 | |||||
daytime rest measurement | 1 | 51.4 | |||||
hematocrit | 2 | 48.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | family with sequence similarity 120B | VGNC:11071 | 465122 | |||||
Macaque | family with sequence similarity 120B | 696010 | ||||||
Mouse | MGI:1914794 | 67544 | ||||||
Rat | RGD:1310304 | 308218 | ||||||
Dog | family with sequence similarity 120B | 612641 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | family with sequence similarity 120B | |||||
Macaque | family with sequence similarity 120B | |||||
Mouse | ||||||
Rat | ||||||
Dog | family with sequence similarity 120B | |||||
PMID | Year | Title |
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