Tbio FAM120B Constitutive coactivator of peroxisome proliferator-activated receptor gamma

Protein Summary

Description

Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity).

Uniprot Accession IDs

• Q96EK7
• B4DL34
• Q86V68
• Q96JI9
• Constitutive coactivator of PPAR-gamma

Gene Name

• FAM120B

Ensembl ID

• ENST00000476287
• ENSP00000417970
• ENSG00000112584
• ENST00000616072
• ENSP00000482544
• ENSG00000275333
• ENST00000617082
• ENSP00000481344
• ENST00000625626
• ENSP00000485793

Symbol

• CCPG
• KIAA1838
• CCPG
• PGCC1
• KIAA1838
• dJ894D12.1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.98
kinase perturbation	0.88
histone modification site profile	0.78
transcription factor binding site profile	0.74
tissue sample	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.55   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 84   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.55   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0