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Tdark
YIPF6
Protein YIPF6

Protein Summary
Description
May be required for stable YIPF1 and YIPF2 protein expression.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374622
  • ENSP00000363751
  • ENSG00000181704
  • ENST00000462683
  • ENSP00000417573

Symbol
  • FinGER6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
transcription factor perturbation
0.91
histone modification site profile
0.87
kinase perturbation
0.76
microRNA
0.67


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.35   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.35   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (116)
YIPF1
Tbio
Novelty:  0.00507381
p_int:  0.9851726
p_ni:  0.014534758
p_wrong:  0.000292643
Score:  0.964
Data Source:  BioPlex,STRINGDB
SLC7A1
Tbio
Family:  Transporter
Novelty:  0.00197313
p_int:  0.901820272
p_ni:  0.098179684
p_wrong:  4.4e-8
Data Source:  BioPlex
SLC7A14
Tbio
Family:  Transporter
Novelty:  0.1613451
p_int:  0.867089035
p_ni:  0.128998332
p_wrong:  0.003912633
Data Source:  BioPlex
ADGRE5
Tbio
Family:  GPCR
Novelty:  0.01137558
p_int:  0.816704618
p_ni:  0.183295024
p_wrong:  3.59e-7
Score:  0.181
Data Source:  BioPlex,STRINGDB
SPPL2B
Tchem
Family:  Enzyme
Novelty:  0.0274774
p_int:  0.803968276
p_ni:  0.196031384
p_wrong:  3.41e-7
Score:  0.156
Data Source:  BioPlex,STRINGDB
YIPF2
Tdark
Novelty:  0.01302483
Score:  0.973
Data Source:  STRINGDB
AP4E1
Tdark
Novelty:  0.09773225
Score:  0.941
Data Source:  STRINGDB
YIPF3
Tbio
Novelty:  0.12021667
Score:  0.933
Data Source:  STRINGDB
OCRL
Tbio
Family:  Enzyme
Novelty:  0.00555539
Score:  0.931
Data Source:  STRINGDB
TBC1D8B
Tdark
Novelty:  0.35419125
Score:  0.925
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Golgi Associated Vesicle Biogenesis (R-HSA-432722)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Golgi Associated Vesicle Biogenesis
Reactome
Membrane Trafficking
Reactome
Vesicle-mediated transport
Reactome
trans-Golgi Network Vesicle Budding
Name
Explore in Pharos
Explore in Source
Golgi Associated Vesicle Biogenesis
Membrane Trafficking
Vesicle-mediated transport
trans-Golgi Network Vesicle Budding
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
1
1
39.4
testosterone measurement
1
1
1
37.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
balding measurement
1
39.4
testosterone measurement
1
37.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
Yip1 domain family member 6
713477
Mouse
MGI:1925179
77929
Rat
RGD:1566154
363476
Dog
Yip1 domain family member 6
VGNC:48492
491931
Horse
Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]
Species
Name
OMA
EggNOG
Inparanoid
Macaque
Yip1 domain family member 6
Mouse
Rat
Dog
Yip1 domain family member 6
Horse
Yip1 domain family member 6 [Source:HGNC Symbol;Acc:HGNC:28304]
Publication Statistics
PubMed Score 10.35
PubMed score by year
PubTator Score 6.20
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title