Protein Summary
Binds lactose. May participate in the apoptosis of adipocytes. This gene encodes a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. The related mouse protein is a primary regulator of the early stages of adipose tissue development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
- ENST00000255684
- ENSP00000255684
- ENSG00000133317
- ENST00000340246
- ENSP00000339374
- ENST00000394618
- ENSP00000378116
- ENST00000415491
- ENSP00000394659
- ENST00000425950
- ENSP00000399093
- GRIP1
- GAL12
- GRIP1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
tissue sample | 0.71 | ||
PubMedID | 0.57 | ||
transcription factor | 0.57 | ||
cell type or tissue | 0.54 | ||
phenotype | 0.47 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.09 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 108 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 24.09 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 108 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0