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Tbio
MUCL1
Mucin-like protein 1

Protein Summary
Description
May play a role as marker for the diagnosis of metastatic breast cancer.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000308796
  • ENSP00000311364
  • ENSG00000172551

Symbol
  • SBEM
  • SBEM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease
0.56
cell line
0.52
cellular component
0.49
protein complex
0.41
biological term
0.36


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.26   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 15   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.26   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 15   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
childhood onset asthma
2
1
0
1.2
56.2
Eczema
1
1
0
1.1
50.6
1
1
0
1.1
50.6
2
1
0
1.1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
childhood onset asthma
0
1.2
56.2
Eczema
0
1.1
50.6
0
1.1
50.6
0
1.1
33.1
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
mucin like 1
VGNC:52070
451964
Species
Name
OMA
EggNOG
Inparanoid
Chimp
mucin like 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96DR8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (15)
C-type lectin receptors (CLRs) (R-HSA-5621481)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 15
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
C-type lectin receptors (CLRs)
Reactome
Dectin-2 family
Reactome
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Reactome
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Reactome
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Name
Explore in Pharos
Explore in Source
C-type lectin receptors (CLRs)
Dectin-2 family
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Gene Ontology Terms (5)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Traceable Author Statement (TAS)
Reactome
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (81)
1 – 10 of 81
PDIA5
Tbio
Family:  Enzyme
Novelty:  0.06234465
p_int:  0.998385794
p_ni:  0.001614206
Data Source:  BioPlex
ATP2B2
Tbio
Family:  Transporter
Novelty:  0.007782
p_int:  0.96250988
p_ni:  0.024084466
p_wrong:  0.013405654
Data Source:  BioPlex
EMC4
Tbio
Novelty:  0.12174476
p_int:  0.894767921
p_ni:  0.029825916
p_wrong:  0.075406163
Data Source:  BioPlex
HVCN1
Tchem
Family:  IC
Novelty:  0.00195009
p_int:  0.87123605
p_ni:  0.128761793
p_wrong:  0.000002156
Score:  0.228
Data Source:  BioPlex,STRINGDB
TLR1
Tbio
Novelty:  0.00171909
p_int:  0.863611786
p_ni:  0.116509775
p_wrong:  0.019878439
Data Source:  BioPlex
ARHGAP36
Tbio
Family:  Enzyme
Novelty:  0.33342126
p_int:  0.860976385
p_ni:  0.139002383
p_wrong:  0.000021232
Score:  0.365
Data Source:  BioPlex,STRINGDB
SPACA9
Tdark
Novelty:  1.56900253
p_int:  0.832942602
p_ni:  0.166991255
p_wrong:  0.000066143
Score:  0.303
Data Source:  BioPlex,STRINGDB
KIAA0355
Tdark
Novelty:  0.97113831
p_int:  0.766267172
p_ni:  0.233715956
p_wrong:  0.000016873
Score:  0.228
Data Source:  BioPlex,STRINGDB
DHX57
Tdark
Family:  Enzyme
Novelty:  0.8244078
p_int:  0.750338998
p_ni:  0.249594128
p_wrong:  0.000066873
Data Source:  BioPlex
SCGB2A2
Tbio
Novelty:  0.01594053
Score:  0.954
Data Source:  STRINGDB
Publication Statistics
PubMed Score  17.26

PubMed score by year
PubTator Score  24.45

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer