OTUB2
Ubiquitin thioesterase OTUB2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.68 | ||
tissue sample | 0.68 | ||
microRNA | 0.67 | ||
virus perturbation | 0.64 | ||
small molecule perturbation | 0.63 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Deubiquitination | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Ovarian tumor domain proteases | ||||
Reactome | Post-translational protein modification | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Deubiquitination | ||||
Metabolism of proteins | ||||
Ovarian tumor domain proteases | ||||
Post-translational protein modification | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
eosinophil count | 3 | 2 | 4 | 88.5 | ||||||
eosinophil count | 3 | 2 | 4 | 88.5 | ||||||
eosinophil percentage of leukocytes | 2 | 2 | 3 | 86.1 | ||||||
eosinophil percentage of leukocytes | 2 | 2 | 3 | 86.1 | ||||||
sum of eosinophil and basophil counts | 1 | 1 | 1 | 72.5 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 4 | 88.5 | |||||
eosinophil count | 4 | 88.5 | |||||
eosinophil percentage of leukocytes | 3 | 86.1 | |||||
eosinophil percentage of leukocytes | 3 | 86.1 | |||||
sum of eosinophil and basophil counts | 1 | 72.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | OTU deubiquitinase, ubiquitin aldehyde binding 2 | 467539 | ||||||
Macaque | OTU deubiquitinase, ubiquitin aldehyde binding 2 | 706795 | ||||||
Mouse | MGI:1915399 | 68149 | ||||||
Rat | RGD:1306688 | 314405 | ||||||
Dog | OTU deubiquitinase, ubiquitin aldehyde binding 2 | VGNC:44183 | 480420 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | OTU deubiquitinase, ubiquitin aldehyde binding 2 | |||||
Macaque | OTU deubiquitinase, ubiquitin aldehyde binding 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | OTU deubiquitinase, ubiquitin aldehyde binding 2 | |||||
PMID | Year | Title |
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