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Tbio
ZG16B
Zymogen granule protein 16 homolog B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382280
  • ENSP00000371715
  • ENSG00000162078
  • ENST00000634500
  • ENSP00000489035
  • ENSG00000283056

Symbol
  • EECP
  • PAUF
  • JCLN2
  • HRPE773
  • PRO1567
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.88
cellular component
0.46
disease
0.45
biological term
0.43
protein complex
0.43


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.72   (req: < 5)
Gene RIFs: 18   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.72   (req: >= 5)
Gene RIFs: 18   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (14)
Items per page:
1 – 5 of 14
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
3
3
3
93.4
eosinophil count
3
3
3
93.4
eosinophil percentage of leukocytes
2
2
2
87.5
eosinophil percentage of leukocytes
2
2
2
87.5
body height
1
1
1
65.5
Items per page:
1 – 5 of 14
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
3
93.4
eosinophil count
3
93.4
eosinophil percentage of leukocytes
2
87.5
eosinophil percentage of leukocytes
2
87.5
body height
1
65.5
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
zymogen granule protein 16B
698097
Dog
zymogen granule protein 16B
VGNC:54092
490055
Horse
zymogen granule protein 16B
VGNC:52109
106781569
Species
Name
OMA
EggNOG
Inparanoid
Macaque
zymogen granule protein 16B
Dog
zymogen granule protein 16B
Horse
zymogen granule protein 16B
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q96DA0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (55)
1 – 10 of 55
ZNF423
Tbio
Family:  TF
Novelty:  0.01718703
p_int:  0.999999864
p_ni:  1.35e-7
p_wrong:  1e-9
Score:  0.177
Data Source:  BioPlex,STRINGDB
SARM1
Tchem
Novelty:  0.00510488
p_int:  0.999999066
p_ni:  9.34e-7
Data Source:  BioPlex
DDI2
Tbio
Novelty:  0.09288646
p_int:  0.999994493
p_ni:  0.000005507
Data Source:  BioPlex
RSC1A1
Tbio
Novelty:  0.23664927
p_int:  0.999950806
p_ni:  1.04e-7
p_wrong:  0.00004909
Score:  0.187
Data Source:  BioPlex,STRINGDB
FRMD1
Tdark
Novelty:  0.96833141
p_int:  0.999367912
p_ni:  0.000632088
Data Source:  BioPlex
SNW1
Tbio
Novelty:  0.01423797
p_int:  0.996747122
p_ni:  0.003252878
Data Source:  BioPlex
DDX31
Tbio
Family:  Enzyme
Novelty:  2.84646195
p_int:  0.996542654
p_ni:  0.003457303
p_wrong:  4.3e-8
Data Source:  BioPlex
NPB
Tdark
Novelty:  0.00936692
p_int:  0.995732618
p_ni:  0.004267382
Data Source:  BioPlex
SLIRP
Tbio
Novelty:  0.04630917
p_int:  0.995692937
p_ni:  0.004307063
Data Source:  BioPlex
KIR2DS2
Tdark
p_int:  0.992614464
p_ni:  0.007385532
p_wrong:  3e-9
Data Source:  BioPlex
Publication Statistics
PubMed Score  11.72

PubMed score by year
PubTator Score  21.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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