RNF183
E3 ubiquitin-protein ligase RNF183
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
virus perturbation | 0.85 | ||
tissue sample | 0.75 | ||
gene perturbation | 0.65 | ||
protein domain | 0.41 | ||
tissue | 0.41 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
UniProt | Protein modification; protein ubiquitination. | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Protein modification; protein ubiquitination. | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
blood lead measurement | 1 | 2 | 2 | 72.4 | |||||
neutrophil count | 1 | 1 | 1 | 69.4 | |||||
reticulocyte measurement | 2 | 1 | 2 | 62.1 | |||||
myeloid white cell count | 1 | 1 | 1 | 61.4 | |||||
reticulocyte count | 2 | 1 | 2 | 60.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
blood lead measurement | 2 | 72.4 | |||||
neutrophil count | 1 | 69.4 | |||||
reticulocyte measurement | 2 | 62.1 | |||||
myeloid white cell count | 1 | 61.4 | |||||
reticulocyte count | 2 | 60.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ring finger protein 183 | VGNC:4850 | 464672 | |||||
Macaque | ring finger protein 183 | 705679 | ||||||
Mouse | MGI:1923322 | 76072 | ||||||
Rat | RGD:1564412 | 500474 | ||||||
Horse | ring finger protein 183 | VGNC:22458 | 100050237 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ring finger protein 183 | |||||
Macaque | ring finger protein 183 | |||||
Mouse | ||||||
Rat | ||||||
Horse | ring finger protein 183 | |||||
PMID | Year | Title |
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