GPRASP2
G-protein coupled receptor-associated sorting protein 2
Protein Summary
May play a role in regulation of a variety of G-protein coupled receptors. This locus represents naturally occurring readthrough transcription among the adjacent armadillo repeat containing, X-linked 5 (ARMCX5), G protein-coupled receptor associated sorting proteins 1 and 2 (GPRASP1 and GPRASP2), basic helix-loop-helix family member b9 (BHLHB9), and long intergenic non-protein coding RNA 630 (LINC00630) genes on chromosome X. Transcripts may make use of multiple alternative promoters and polyadenylation signals in this region. Readthrough transcripts may produce proteins identical to the proteins encoded by GPRASP2 or BHLHB9. [provided by RefSeq, Apr 2017]
- ENST00000332262
- ENSP00000339057
- ENSG00000158301
- ENST00000535209
- ENSP00000437394
- ENST00000543253
- ENSP00000437872
- bHLHb9
- p60TRP
- ARMCX5-GPRASP2-BHLHB9-LINC00630
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
tissue sample | 0.65 | ||
tissue | 0.52 | ||
small molecule perturbation | 0.48 | ||
transcription factor perturbation | 0.47 | ||
PubMedID | 0.45 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.04 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 182 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.04 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 182 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0