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Tbio
TUBGCP3
Gamma-tubulin complex component 3

Protein Summary
Description
Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261965
  • ENSP00000261965
  • ENSG00000126216
  • ENST00000375669
  • ENSP00000364821

Symbol
  • GCP3
  • 104p
  • ALP6
  • GCP3
  • Spc98
  • SPBC98
  • Spc98p
  • Grip104
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.93
histone modification site profile
0.89
transcription factor binding site profile
0.76
cellular component
0.65
transcription factor
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 43.51   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 196   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 43.51   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 196   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (190)
ANXA13
Tbio
Novelty:  0.01534307
p_int:  0.999998634
p_ni:  0.000001366
Score:  0.234
Data Source:  BioPlex,STRINGDB
MZT1
Tdark
Novelty:  0.06713659
p_int:  0.999972335
p_ni:  0.000027665
Score:  0.999
Data Source:  BioPlex,STRINGDB
TUBGCP5
Tbio
Novelty:  0.04863776
p_int:  0.999948615
p_ni:  0.000051385
Score:  0.995
Data Source:  BioPlex,STRINGDB
TUBG2
Tbio
Novelty:  0.14828466
p_int:  0.999859712
p_ni:  0.000140288
Score:  0.997
Data Source:  BioPlex,Reactome,STRINGDB
MZT2B
Tdark
Novelty:  0.69469786
p_int:  0.999814566
p_ni:  0.000185434
Score:  0.995
Data Source:  BioPlex,STRINGDB
TXNDC12
Tbio
Novelty:  0.01354011
p_int:  0.99879529
p_ni:  0.00120471
Score:  0.71
Data Source:  BioPlex,STRINGDB
APLNR
Tchem
Family:  GPCR
Novelty:  0.00224203
p_int:  0.993044316
p_ni:  0.006955684
Data Source:  BioPlex
LGALS3BP
Tbio
Novelty:  0.0025302
p_int:  0.973828192
p_ni:  0.026171808
Score:  0.535
Data Source:  BioPlex,STRINGDB
CD79B
Tclin
Novelty:  0.00227414
p_int:  0.944424086
p_ni:  0.055575914
Data Source:  BioPlex
CMKLR1
Tchem
Family:  GPCR
Novelty:  0.00893083
p_int:  0.914273366
p_ni:  0.085726634
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (9)
Cell Cycle (R-HSA-1640170)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 9
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cell Cycle
Reactome
Cell Cycle, Mitotic
Reactome
Centrosome maturation
Reactome
G2/M Transition
Reactome
M Phase
Name
Explore in Pharos
Explore in Source
Cell Cycle
Cell Cycle, Mitotic
Centrosome maturation
G2/M Transition
M Phase
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
4
4
4
93.6
red blood cell distribution width
3
1
3
87.3
red blood cell density measurement
1
1
1
68.6
mean corpuscular volume
1
1
1
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
4
93.6
red blood cell distribution width
3
87.3
red blood cell density measurement
1
68.6
mean corpuscular volume
1
38.8
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 3
VGNC:7306
452676
Macaque
tubulin gamma complex associated protein 3
721894
Mouse
MGI:2183752
259279
Rat
RGD:1305726
306599
Dog
tubulin gamma complex associated protein 3
VGNC:47993
476991
Species
Name
OMA
EggNOG
Inparanoid
Chimp
tubulin gamma complex associated protein 3
Macaque
tubulin gamma complex associated protein 3
Mouse
Rat
Dog
tubulin gamma complex associated protein 3
Publication Statistics
PubMed Score 43.51
PubMed score by year
PubTator Score 9.66
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title