Tbio GCC1 GRIP and coiled-coil domain-containing protein 1

Protein Summary

Description

Probably involved in maintaining Golgi structure. The protein encoded by this gene is a peripheral membrane protein. It is sensitive to brefeldin A. This encoded protein contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q96CN9
• Q9H6N7

Gene Name

• GCC1

Ensembl ID

• ENST00000321407
• ENSP00000318821
• ENSG00000179562

Symbol

• GCC1P
• GCC88

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.75
histone modification site profile	0.72
disease perturbation	0.62
microRNA	0.61
virus perturbation	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.41   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 151   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.41   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 151   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0