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Tbio
EVI5L
EVI5-like protein

Protein Summary
Description
Functions as a GTPase-activating protein (GAP) with a broad specificity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000270530
  • ENSP00000270530
  • ENSG00000142459
  • ENST00000538904
  • ENSP00000445905
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor
0.81
histone modification site profile
0.68
cell type or tissue
0.67
tissue sample
0.64
transcription factor binding site profile
0.57


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.91   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menarche
1
1
1
29.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menarche
1
29.7
Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Physical Interaction (IPI)
UniProtKB
Protein-Protein Interactions (41)
1 – 10 of 41
FIS1
Tbio
Novelty: 0.0033607
p_int: 0.999840221
p_ni: 0.000158733
p_wrong: 0.000001046
Data Source: BioPlex
FAF2
Tbio
Novelty: 0.03048598
p_int: 0.999443557
p_ni: 0.000556422
p_wrong: 2.1e-8
Data Source: BioPlex
RAB43
Tbio
Family: Enzyme
Novelty: 0.07527576
p_int: 0.99926925
p_ni: 0.000729157
p_wrong: 0.000001593
Score: 0.328
Data Source: BioPlex,STRINGDB
SIGLECL1
Tdark
p_int: 0.997690436
p_ni: 0.002267725
p_wrong: 0.00004184
Data Source: BioPlex
FZD10
Tbio
Family: GPCR
Novelty: 0.02786933
p_int: 0.997249611
p_ni: 0.00267351
p_wrong: 0.00007688
Data Source: BioPlex
NPY2R
Tchem
Family: GPCR
Novelty: 0.01177255
p_int: 0.997028748
p_ni: 0.001127386
p_wrong: 0.001843865
Data Source: BioPlex
PTGER3
Tclin
Family: GPCR
Novelty: 0.0012681
p_int: 0.996778055
p_ni: 0.00311522
p_wrong: 0.000106726
Data Source: BioPlex
C5AR2
Tbio
Family: GPCR
Novelty: 0.01193736
p_int: 0.995838675
p_ni: 0.00411629
p_wrong: 0.000045034
Data Source: BioPlex
TSPYL1
Tbio
Novelty: 0.06381144
p_int: 0.994827188
p_ni: 0.004620138
p_wrong: 0.000552675
Data Source: BioPlex
P2RX2
Tchem
Family: IC
Novelty: 0.00241146
p_int: 0.982676106
p_ni: 0.01616645
p_wrong: 0.001157444
Data Source: BioPlex
Publication Statistics
PubMed Score  1.91

PubMed score by year
PubTator Score  0.7

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer