Tbio ARL8A ADP-ribosylation factor-like protein 8A

Protein Summary

Description

May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity).

Uniprot Accession IDs

• Q96BM9
• B3KXD0

Gene Name

• ARL8A

Ensembl ID

• ENST00000272217
• ENSP00000272217
• ENSG00000143862

Symbol

• ARL10B
• GIE2
• GIE2
• ARL10B

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.96
interacting protein	0.87
kinase perturbation	0.76
transcription factor perturbation	0.74
cellular component	0.73

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.35   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 214   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.35   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 214   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0