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Tbio
SLCO4A1
Solute carrier organic anion transporter family member 4A1

Protein Summary
Description
Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000217159
  • ENSP00000217159
  • ENSG00000101187
  • ENST00000370507
  • ENSP00000359538

Symbol
  • OATP1
  • OATP4A1
  • OATPE
  • SLC21A12
  • POAT
  • OATP1
  • OATPE
  • OATP-E
  • OATP4A1
  • OATPRP1
  • SLC21A12
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.97
transcription factor perturbation
0.91
PubMedID
0.8
kinase perturbation
0.76
tissue
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.97   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 31   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.97   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 31   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0