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Tdark
ZNF428
Zinc finger protein 428

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000300811
  • ENSP00000300811
  • ENSG00000131116

Symbol
  • C19orf37
  • Zfp428
  • C19orf37
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
transcription factor binding site profile
0.83
transcription factor perturbation
0.74
cellular component
0.73
small molecule perturbation
0.7


Related Tools
GENEVA
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GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.21   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 84   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.21   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 84   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 428
VGNC:11541
742971
Mouse
MGI:1916463
232969
Rat
RGD:1564862
361519
Dog
zinc finger protein 428
VGNC:48725
611184
Cow
zinc finger protein 428
VGNC:37274
540173
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 428
Mouse
Rat
Dog
zinc finger protein 428
Cow
zinc finger protein 428
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96B54-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (40)
1 – 10 of 40
CHAMP1
Tbio
Novelty: 0.09520274
p_int: 0.999999941
p_ni: 1.9e-8
p_wrong: 4e-8
Score: 0.188
Data Source: BioPlex,STRINGDB
POGZ
Tbio
Novelty: 0.03603188
p_int: 0.999999804
p_ni: 1.29e-7
p_wrong: 6.7e-8
Score: 0.188
Data Source: BioPlex,STRINGDB
FOXK2
Tbio
Family: TF
Novelty: 0.01420141
p_int: 0.999993118
p_ni: 0.000006882
Data Source: BioPlex
FOXK1
Tbio
Family: TF
Novelty: 0.01321144
p_int: 0.99994598
p_ni: 0.00005402
Data Source: BioPlex
PIP4K2C
Tchem
Family: Kinase
Novelty: 0.11466436
p_int: 0.992649293
p_ni: 0.007350694
p_wrong: 1.3e-8
Score: 0.213
Data Source: BioPlex,STRINGDB
PARP2
Tclin
Family: Enzyme
Novelty: 0.00545618
p_int: 0.971818069
p_ni: 0.028181914
p_wrong: 1.6e-8
Data Source: BioPlex
PIP4K2B
Tchem
Family: Kinase
Novelty: 0.06261627
p_int: 0.947708427
p_ni: 0.052290426
p_wrong: 0.000001147
Score: 0.305
Data Source: BioPlex,STRINGDB
H2AFY
Tbio
Novelty: 0.01150729
p_int: 0.866706727
p_ni: 0.133260885
p_wrong: 0.000032387
Score: 0.237
Data Source: BioPlex,STRINGDB
GTF2I
Tbio
Family: TF
Novelty: 0.00703345
p_int: 0.82453315
p_ni: 0.175466849
p_wrong: 2e-9
Score: 0.19
Data Source: BioPlex,STRINGDB
XPC
Tbio
Novelty: 0.00775175
p_int: 0.804735643
p_ni: 0.195264357
Score: 0.542
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  0.21

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer