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Tbio
VOPP1
Vesicular, overexpressed in cancer, prosurvival protein 1

Protein Summary
Description
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000285279
  • ENSP00000285279
  • ENSG00000154978
  • ENST00000418904
  • ENSP00000393210
  • ENST00000433959
  • ENSP00000415230
  • ENST00000625836
  • ENSP00000486983

Symbol
  • ECOP
  • GASP
  • ECOP
  • GASP
  • WBP1L2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
transcription factor binding site profile
0.8
cell type or tissue
0.76
PubMedID
0.73
kinase perturbation
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.2   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 47.2   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (19)
LANCL2
Tchem
Novelty:  0.06086418
Score:  0.728
Data Source:  STRINGDB
CYYR1
Tbio
Novelty:  0.19732526
Score:  0.713
Data Source:  STRINGDB
WBP1
Tbio
Novelty:  1.24967974
Score:  0.71
Data Source:  STRINGDB
VWA7
Tdark
Novelty:  0.15513587
Score:  0.669
Data Source:  STRINGDB
TMEM207
Tdark
Novelty:  0.35957705
Score:  0.625
Data Source:  STRINGDB
SHISAL1
Tdark
Novelty:  0.66511357
Score:  0.61
Data Source:  STRINGDB
VSTM2A
Tbio
Novelty:  0.34891628
Score:  0.579
Data Source:  STRINGDB
ZNF713
Tdark
Family:  TF
Novelty:  0.53817745
Score:  0.546
Data Source:  STRINGDB
ARMC10
Tbio
Novelty:  0.08714295
Score:  0.528
Data Source:  STRINGDB
SEC61G
Tbio
Novelty:  0.11375671
Score:  0.507
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
VOPP1, WBP1/VOPP1 family member
VGNC:4561
741927
Macaque
VOPP1, WBP1/VOPP1 family member
716151
Mouse
MGI:2141658
232023
Rat
RGD:1306494
362374
Dog
VOPP1, WBP1/VOPP1 family member
VGNC:54387
608562
Species
Name
OMA
EggNOG
Inparanoid
Chimp
VOPP1, WBP1/VOPP1 family member
Macaque
VOPP1, WBP1/VOPP1 family member
Mouse
Rat
Dog
VOPP1, WBP1/VOPP1 family member
Publication Statistics
PubMed Score 47.20
PubMed score by year
PubTator Score 14.33
PubTator score by year
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Related Publications
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PMID
Year
Title