Tbio JAKMIP2 Janus kinase and microtubule-interacting protein 2

Protein Summary

Description

The protein encoded by this gene is reported to be a component of the Golgi matrix. It may act as a golgin protein by negatively regulating transit of secretory cargo and by acting as a structural scaffold of the Golgi. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Accession IDs

• Q96AA8
• A4ZZA7
• A8K5G5
• B4DSG0
• G5E9Y0
• O60302
• Q548S1

Gene Name

• JAKMIP2

Ensembl ID

• ENST00000265272
• ENSP00000265272
• ENSG00000176049
• ENST00000333010
• ENSP00000328989
• ENST00000507386
• ENSP00000421398
• ENST00000616793
• ENSP00000479248

Symbol

• JAMIP2
• KIAA0555
• NECC1
• NECC1
• JAMIP2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.72
interacting protein	0.57
tissue	0.56
cell type or tissue	0.54
tissue sample	0.5

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.28   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 187   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.28   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 187   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0