RFT1
Protein RFT1 homolog
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.9 | ||
kinase perturbation | 0.76 | ||
microRNA | 0.75 | ||
transcription factor binding site profile | 0.69 | ||
tissue sample | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Asparagine N-linked glycosylation | ||||
Reactome | Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Reactome | Defective RFT1 causes RFT1-CDG (CDG-1n) | ||||
Reactome | Disease | ||||
Reactome | Diseases associated with N-glycosylation of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Asparagine N-linked glycosylation | ||||
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | ||||
Defective RFT1 causes RFT1-CDG (CDG-1n) | ||||
Disease | ||||
Diseases associated with N-glycosylation of proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
urate measurement | 6 | 6 | 8 | 98.5 | |||||
waist-hip ratio | 1 | 7 | 7 | 81.7 | |||||
BMI-adjusted waist-hip ratio | 1 | 8 | 8 | 81.5 | |||||
body height | 3 | 3 | 3 | 80.1 | |||||
waist circumference | 1 | 6 | 6 | 78.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
urate measurement | 8 | 98.5 | |||||
waist-hip ratio | 7 | 81.7 | |||||
BMI-adjusted waist-hip ratio | 8 | 81.5 | |||||
body height | 3 | 80.1 | |||||
waist circumference | 6 | 78.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RFT1 homolog | 460441 | ||||||
Macaque | RFT1 homolog | 694586 | ||||||
Mouse | MGI:3607791 | 328370 | ||||||
Rat | RGD:1562654 | 290552 | ||||||
Dog | RFT1 homolog | 476589 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RFT1 homolog | |||||
Macaque | RFT1 homolog | |||||
Mouse | ||||||
Rat | ||||||
Dog | RFT1 homolog | |||||
PMID | Year | Title |
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