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Tbio
MYLPF
Myosin regulatory light chain 2, skeletal muscle isoform

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 72.54   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 160   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 72.54   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 160   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (39)
Muscle contraction (R-HSA-397014)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Muscle contraction
Reactome
Smooth Muscle Contraction
Name
Explore in Pharos
Explore in Source
Muscle contraction
Smooth Muscle Contraction
Gene Ontology Terms (8)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
BHF-UCL
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (143)
1 – 10 of 143
RSPH6A
Tdark
Novelty: 0.07169275
p_int: 0.999999997
p_ni: 3e-9
Data Source: BioPlex
MECOM
Tbio
Family: TF; Epigenetic
Novelty: 0.00805252
p_int: 0.999999988
p_ni: 1.2e-8
Data Source: BioPlex
ABTB2
Tdark
Novelty: 3.6
p_int: 0.999319305
p_ni: 0.000030837
p_wrong: 0.000649858
Data Source: BioPlex
MYLK
Tchem
Family: Kinase
Novelty: 0.00132404
Score: 0.991
Data Source: STRINGDB
ACTA2
Tbio
Novelty: 0.00281551
Score: 0.985
Data Source: STRINGDB
ACTG2
Tbio
Novelty: 0.00388853
Score: 0.984
Data Source: STRINGDB
MYH11
Tbio
Novelty: 0.00189652
Score: 0.976
Data Source: STRINGDB
MYH1
Tbio
Novelty: 0.00659362
Score: 0.974
Data Source: STRINGDB
ACTA1
Tbio
Novelty: 0.00147233
Score: 0.971
Data Source: STRINGDB
MYL1
Tbio
Novelty: 0.00328181
Score: 0.971
Data Source: STRINGDB
Publication Statistics
PubMed Score  72.54

PubMed score by year
PubTator Score  2.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer