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Tbio
TBRG4
FAST kinase domain-containing protein 4

Protein Summary
Description
Plays a role in processing of mitochondrial RNA precursors and in stabilization of a subset of mature mitochondrial RNA species, such as MT-CO1, MT-CO2, MT-CYB, MT-CO3, MT-ND3, MT-ND5 and MT-ATP8/6. May play a role in cell cycle progression (PubMed:9383053).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258770
  • ENSP00000258770
  • ENSG00000136270
  • ENST00000361278
  • ENSP00000354992
  • ENST00000395655
  • ENSP00000379016
  • ENST00000494076
  • ENSP00000420597

Symbol
  • CPR2
  • FASTKD4
  • KIAA0948
  • CPR2
  • FASTKD4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.95
transcription factor binding site profile
0.91
histone modification site profile
0.85
kinase perturbation
0.84
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.37   (req: < 5)
Gene RIFs: 11   (req: <= 3)
Antibodies: 166   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.37   (req: >= 5)
Gene RIFs: 11   (req: > 3)
Antibodies: 166   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0