L3MBTL2
Lethal(3)malignant brain tumor-like protein 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.71 | ||
histone modification site profile | 0.69 | ||
tissue sample | 0.68 | ||
transcription factor | 0.59 | ||
tissue | 0.56 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Generic Transcription Pathway | ||||
Reactome | Metabolism of proteins | ||||
Reactome | Post-translational protein modification | ||||
Reactome | RNA Polymerase II Transcription | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Gene expression (Transcription) | ||||
Generic Transcription Pathway | ||||
Metabolism of proteins | ||||
Post-translational protein modification | ||||
RNA Polymerase II Transcription | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
4 | 3 | 2 | 1 | 94.8 | |||||
neuroticism measurement | 6 | 6 | 4 | 7 | 89.4 | ||||
1 | 2 | 0 | 5.9 | 88.5 | |||||
risk-taking behaviour | 2 | 4 | 4 | 84.3 | |||||
red blood cell distribution width | 2 | 2 | 2 | 83.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
2 | 1 | 94.8 | |||||
neuroticism measurement | 4 | 7 | 89.4 | ||||
0 | 5.9 | 88.5 | |||||
risk-taking behaviour | 4 | 84.3 | |||||
red blood cell distribution width | 2 | 83.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | L3MBTL2, polycomb repressive complex 1 subunit | VGNC:10088 | 458863 | |||||
Macaque | L3MBTL2, polycomb repressive complex 1 subunit | 706602 | ||||||
Mouse | MGI:2443584 | 214669 | ||||||
Rat | RGD:1308569 | 300320 | ||||||
Dog | L3MBTL2, polycomb repressive complex 1 subunit | VGNC:42558 | 481235 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | L3MBTL2, polycomb repressive complex 1 subunit | |||||
Macaque | L3MBTL2, polycomb repressive complex 1 subunit | |||||
Mouse | ||||||
Rat | ||||||
Dog | L3MBTL2, polycomb repressive complex 1 subunit | |||||
PMID | Year | Title |
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