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Tbio
RAB24
Ras-related protein Rab-24

Protein Summary
Description
May be involved in autophagy-related processes. RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000303251
  • ENSP00000304376
  • ENSG00000169228
  • ENST00000393611
  • ENSP00000377235
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
molecular function
0.91
tissue sample
0.74
virus perturbation
0.72
transcription factor binding site profile
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.74   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 242   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.74   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 242   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (125)
1 – 10 of 125
GDI1
Tbio
Novelty:  0.01710945
p_int:  0.999999986
p_ni:  2e-9
p_wrong:  1.2e-8
Score:  0.606
Data Source:  BioPlex,STRINGDB
FIS1
Tbio
Novelty:  0.0033607
p_int:  0.999999936
p_ni:  6.4e-8
Data Source:  BioPlex
RAB7A
Tchem
Family:  Enzyme
Novelty:  0.00192702
Score:  0.937
Data Source:  STRINGDB
RAB7B
Tbio
Family:  Enzyme
Novelty:  0.00207354
Score:  0.935
Data Source:  STRINGDB
CHM
Tbio
Family:  Enzyme
Novelty:  0.00226278
Score:  0.933
Data Source:  STRINGDB
RAB9A
Tbio
Family:  Enzyme
Novelty:  0.07006531
Score:  0.933
Data Source:  STRINGDB
RAB34
Tbio
Novelty:  0.03645677
Score:  0.932
Data Source:  STRINGDB
RAB34
Tbio
Family:  Enzyme
Novelty:  0.03645677
Score:  0.932
Data Source:  STRINGDB
CHML
Tbio
Family:  Enzyme
Novelty:  0.00509709
Score:  0.931
Data Source:  STRINGDB
RAB33B
Tbio
Family:  Enzyme
Novelty:  0.06381712
Score:  0.93
Data Source:  STRINGDB
Pathways (6)
Immune System (R-HSA-168256)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Immune System
Reactome
Innate Immune System
Reactome
Metabolism of proteins
Reactome
Neutrophil degranulation
Reactome
Post-translational protein modification
Name
Explore in Pharos
Explore in Source
Immune System
Innate Immune System
Metabolism of proteins
Neutrophil degranulation
Post-translational protein modification
Gene Ontology Terms (12)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (47)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
9
7
10
15.2
99.2
creatinine measurement
5
5
6
96.7
hematocrit
5
5
5
96.1
hemoglobin measurement
4
4
4
94.3
body weights and measures
1
2
2
94
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
10
15.2
99.2
creatinine measurement
6
96.7
hematocrit
5
96.1
hemoglobin measurement
4
94.3
body weights and measures
2
94
Find similar targets by:
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RAB24, member RAS oncogene family
VGNC:8633
471755
Macaque
RAB24, member RAS oncogene family
698876
Mouse
MGI:105065
19336
Dog
RAB24, member RAS oncogene family
VGNC:45264
479277
Horse
RAB24, member RAS oncogene family
VGNC:22097
100058530
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RAB24, member RAS oncogene family
Macaque
RAB24, member RAS oncogene family
Mouse
Dog
RAB24, member RAS oncogene family
Horse
RAB24, member RAS oncogene family
Publication Statistics
PubMed Score 22.74
PubMed score by year
PubTator Score 9.38
PubTator score by year