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Tbio
RPL36AL
60S ribosomal protein L36a-like

Protein Summary
Description
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. This gene and the human gene officially named ribosomal protein L36a (RPL36A) encode nearly identical proteins; however, they are distinct genes. Although the name of this gene has been referred to as ribosomal protein L36a (RPL36A), its official name is ribosomal protein L36a-like (RPL36AL). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298289
  • ENSP00000346012
  • ENSG00000165502

Symbol
  • RPL36A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.85
co-expressed gene
0.79
interacting protein
0.78
kinase perturbation
0.76
transcription factor binding site profile
0.76


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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.2   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.2   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Platypus
60S ribosomal protein L36a
100082971
Anole lizard
60S ribosomal protein L36a
100561390
Xenopus
ribosomal protein L36a
XB-GENE-974799
448673
Zebrafish
ZDB-GENE-020423-1
195819
Species
Name
OMA
EggNOG
Inparanoid
Platypus
60S ribosomal protein L36a
Anole lizard
60S ribosomal protein L36a
Xenopus
ribosomal protein L36a
Zebrafish
Pathways (33)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (356)
1 – 10 of 356
SETD6
Tbio
Family: Epigenetic
Novelty: 0.091198
p_int: 0.999999955
p_ni: 3.6e-8
p_wrong: 1e-8
Score: 0.453
Data Source: BioPlex,STRINGDB
NAP1L1
Tbio
Novelty: 0.03895314
p_int: 0.999909617
p_ni: 0.000090383
Score: 0.247
Data Source: BioPlex,STRINGDB
SDAD1
Tdark
Novelty: 0.2574139
p_int: 0.999893983
p_ni: 0.000106017
Data Source: BioPlex
RBM34
Tdark
Novelty: 0.58131282
p_int: 0.999190233
p_ni: 0.000809734
p_wrong: 3.3e-8
Score: 0.225
Data Source: BioPlex,STRINGDB
SHCBP1
Tbio
Novelty: 0.09160318
p_int: 0.998874148
p_ni: 0.00112584
p_wrong: 1.2e-8
Data Source: BioPlex
RPL14
Tbio
Novelty: 0.01600377
p_int: 0.998489864
p_ni: 0.001510135
Score: 0.997
Data Source: BioPlex,STRINGDB
HIST1H1A
Tbio
Novelty: 0.00123818
p_int: 0.998157482
p_ni: 0.001842509
p_wrong: 1e-8
Score: 0.213
Data Source: BioPlex,STRINGDB
RPL11
Tbio
Novelty: 0.00448962
p_int: 0.997849473
p_ni: 0.002150522
p_wrong: 5e-9
Score: 0.998
Data Source: BioPlex,STRINGDB
HIST1H1T
Tdark
Novelty: 0.01039464
p_int: 0.997102097
p_ni: 0.002897897
p_wrong: 6e-9
Data Source: BioPlex
H1FNT
Tdark
Novelty: 0.05593238
p_int: 0.99709928
p_ni: 0.002900426
p_wrong: 2.93e-7
Data Source: BioPlex
Publication Statistics
PubMed Score  9.20

PubMed score by year
PubTator Score  3

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer