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Tdark
TOMM40L
Mitochondrial import receptor subunit TOM40B

Protein Summary
Description
Potential channel-forming protein implicated in import of protein precursors into mitochondria.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367987
  • ENSP00000356966
  • ENSG00000158882
  • ENST00000367988
  • ENSP00000356967
  • ENST00000545897
  • ENSP00000443233

Symbol
  • TOMM40B
  • TOMM40B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.92
transcription factor binding site profile
0.85
kinase perturbation
0.66
transcription factor
0.66
microRNA
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (128)
1 – 10 of 128
TOMM22
Tbio
Novelty: 0.01708532
p_int: 0.999646298
p_wrong: 0.000353702
Score: 0.921
Data Source: BioPlex,STRINGDB
TOMM7
Tbio
Novelty: 0.06024351
p_int: 0.900772415
p_ni: 4.81e-7
p_wrong: 0.099227104
Score: 0.82
Data Source: BioPlex,STRINGDB
TOMM70
Tbio
Novelty: 0.01497773
Score: 0.865
Data Source: STRINGDB
TOMM20
Tbio
Novelty: 0.00600801
Score: 0.851
Data Source: STRINGDB
SAMM50
Tbio
Novelty: 0.00767957
Score: 0.849
Data Source: STRINGDB
TOMM20L
Tdark
Score: 0.844
Data Source: STRINGDB
SOD1
Tbio
Family: Enzyme
Novelty: 0.00044941
Score: 0.833
Data Source: STRINGDB
TOMM40
Tbio
Novelty: 0.00561476
Score: 0.807
Data Source: STRINGDB
TIMM50
Tbio
Family: Enzyme
Novelty: 0.03118503
Score: 0.801
Data Source: STRINGDB
VDAC3
Tbio
Novelty: 0.01448609
Score: 0.785
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.14

PubMed score by year
PubTator Score  1.78

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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