DVL3
Segment polarity protein dishevelled homolog DVL-3
Protein Summary
Involved in the signal transduction pathway mediated by multiple Wnt genes. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008]
- ENST00000313143
- ENSP00000316054
- ENSG00000161202
- ENST00000431765
- ENSP00000405885
- ENST00000649964
- ENSP00000497134
- KIAA0208
- DRS3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 1 | ||
biological process | 0.84 | ||
microRNA | 0.76 | ||
cell type or tissue | 0.72 | ||
pathway | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 71.04 (req: < 5)
Gene RIFs: 42 (req: <= 3)
Antibodies: 289 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 71.04 (req: >= 5)
Gene RIFs: 42 (req: > 3)
Antibodies: 289 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 21
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0