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Tbio
SNAPC3
snRNA-activating protein complex subunit 3

Protein Summary
Description
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380821
  • ENSP00000370200
  • ENSG00000164975
  • ENST00000467062
  • ENSP00000436699
  • ENST00000490969
  • ENSP00000432393
  • ENST00000610884
  • ENSP00000483273

Symbol
  • SNAP50
  • SNAP50
  • PTFbeta
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.87
histone modification site profile
0.75
PubMedID
0.72
kinase perturbation
0.71
tissue sample
0.63


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.01   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.01   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
small nuclear RNA activating complex polypeptide 3
VGNC:4866
473177
Macaque
small nuclear RNA activating complex polypeptide 3
106992274
Mouse
MGI:1916338
77634
Rat
RGD:1305172
362537
Dog
small nuclear RNA activating complex polypeptide 3
VGNC:51762
611086
Species
Name
OMA
EggNOG
Inparanoid
Chimp
small nuclear RNA activating complex polypeptide 3
Macaque
small nuclear RNA activating complex polypeptide 3
Mouse
Rat
Dog
small nuclear RNA activating complex polypeptide 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q92966-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (7)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
RNA Polymerase II Transcription
Reactome
RNA Polymerase III Abortive And Retractive Initiation
Reactome
RNA Polymerase III Transcription
Reactome
RNA Polymerase III Transcription Initiation
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
RNA Polymerase II Transcription
RNA Polymerase III Abortive And Retractive Initiation
RNA Polymerase III Transcription
RNA Polymerase III Transcription Initiation
Gene Ontology Terms (9)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (127)
1 – 10 of 127
SNAPC1
Tbio
Novelty: 0.18444701
p_int: 0.999999999
Score: 0.999
Data Source: BioPlex,STRINGDB
PSME3
Tbio
Novelty: 0.01051254
p_int: 0.99999763
p_ni: 0.000001516
p_wrong: 8.54e-7
Score: 0.664
Data Source: BioPlex,STRINGDB
ANKRD36B
Tdark
Novelty: 2.44907149
p_int: 0.999983803
p_ni: 0.000012635
p_wrong: 0.000003562
Data Source: BioPlex
SNAPC4
Tbio
Family: TF
Novelty: 0.09720791
Score: 0.995
Data Source: STRINGDB
SNAPC2
Tdark
Novelty: 0.26291137
Score: 0.993
Data Source: STRINGDB
SNAPC5
Tdark
Novelty: 0.61681654
Score: 0.984
Data Source: STRINGDB
TBP
Tbio
Novelty: 0.00034941
Score: 0.961
Data Source: STRINGDB
POLR3H
Tbio
Family: Enzyme
Novelty: 0.16483597
Score: 0.955
Data Source: STRINGDB
BDP1
Tbio
Novelty: 0.00497963
Score: 0.953
Data Source: STRINGDB
POLR3F
Tbio
Family: Enzyme
Novelty: 0.0805125
Score: 0.946
Data Source: STRINGDB
Publication Statistics
PubMed Score  9.01

PubMed score by year
PubTator Score  5.38

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer