SLCO2A1
Solute carrier organic anion transporter family member 2A1
Protein Summary
May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A. This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]
- ENST00000310926
- ENSP00000311291
- ENSG00000174640
- OATP2A1
- SLC21A2
- PGT
- MATR1
- PHOAR2
- OATP2A1
- SLC21A2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
gene perturbation | 0.97 | ||
transcription factor perturbation | 0.91 | ||
PubMedID | 0.84 | ||
tissue sample | 0.71 | ||
cell type or tissue | 0.7 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1197.01 (req: < 5)
Gene RIFs: 50 (req: <= 3)
Antibodies: 59 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1197.01 (req: >= 5)
Gene RIFs: 50 (req: > 3)
Antibodies: 59 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 4
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 1